Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Lin28b KO Male
M
12wk
B6N(Cg)-Lin28b<tm1b(EUCOMM)Hmgu>/J (C57BL/6NTac)
• KO/KO
Lin28b KO Female
F
12wk
B6N(Cg)-Lin28b<tm1b(EUCOMM)Hmgu>/J (C57BL/6NTac)
• KO/KO
Lin28b WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Lin28b WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Lin28b WT Male (Mean ± SD) | Lin28b KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 24.28 ± 2.82 | 22.09 ± 2.07 | 0.1211 |
| Bone Mineral Density (mg/ccm HA) | 1,147.62 ± 4.76 | 1,139.99 ± 4.36 | 0.0074* |
| Cortical Area (mm^2) | 0.716 ± 0.090 | 0.678 ± 0.075 | 0.4027 |
| Cortical Area / Total Area (%) | 41.40 ± 2.41 | 39.09 ± 0.71 | 0.0406* |
| Cortical Mask (dimensionless) | 0.718 ± 0.091 | 0.679 ± 0.076 | 0.4045 |
| Cortical Porosity (%) | 0.243 ± 0.035 | 0.241 ± 0.083 | 0.9481 |
| Cortical Thickness (mm) | 0.1641 ± 0.0090 | 0.1531 ± 0.0088 | 0.0364* |
| Endocortical Perimeter (mm) | 3.57 ± 0.37 | 3.63 ± 0.21 | 0.6974 |
| Length (mm) | 14.75 ± 0.41 | 14.56 ± 0.39 | 0.4132 |
| Marrow Area (mm^2) | 1.03 ± 0.20 | 1.05 ± 0.12 | 0.7522 |
| Maximum Distance from Centroid (mm) | 1.89 ± 0.20 | 1.918 ± 0.094 | 0.7362 |
| Maximum Moment of Inertia (mm^4) | 0.227 ± 0.070 | 0.220 ± 0.050 | 0.8202 |
| Minimum Distance from Centroid (mm) | 1.258 ± 0.087 | 1.234 ± 0.062 | 0.5645 |
| Minimum Moment of Inertia (mm^4) | 0.116 ± 0.032 | 0.108 ± 0.026 | 0.6121 |
| Periosteal Perimeter (mm) | 4.57 ± 0.60 | 4.59 ± 0.45 | 0.9375 |
| Polar Moment of Inertia (mm^4) | 0.34 ± 0.10 | 0.328 ± 0.076 | 0.7485 |
| Pore Area (mm^2) | 0.0018 ± 0.0004 | 0.0017 ± 0.0008 | 0.8584 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.235 ± 0.050 | 0.227 ± 0.040 | 0.7431 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.182 ± 0.039 | 0.174 ± 0.033 | 0.6663 |
| Tissue Mineral Density (mg/ccm HA) | 1,211.00 ± 5.97 | 1,204.50 ± 4.21 | 0.0338* |
| Total Area (mm^2) | 1.74 ± 0.29 | 1.73 ± 0.20 | 0.9451 |