Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Limch1 KO Male
M
12wk
B6N(Cg)-Limch1<1b(EUCOMM)Hmgu>/J (C57BL/6NTac)
• KO/KO
Limch1 KO Female
F
12wk
B6N(Cg)-Limch1<1b(EUCOMM)Hmgu>/J (C57BL/6NTac)
• KO/KO
Limch1 WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Limch1 WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Limch1 WT Male (Mean ± SD) | Limch1 KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 28.21 ± 2.11 | 26.37 ± 2.73 | 0.1801 |
| Bone Mineral Density (mg/ccm HA) | 1,135.37 ± 9.56 | 1,160.58 ± 10.74 | <0.001* |
| Cortical Area (mm^2) | 0.685 ± 0.059 | 0.742 ± 0.059 | 0.0924 |
| Cortical Area / Total Area (%) | 38.71 ± 1.21 | 43.37 ± 1.95 | <0.001* |
| Cortical Mask (dimensionless) | 0.687 ± 0.059 | 0.745 ± 0.060 | 0.0908 |
| Cortical Porosity (%) | 0.249 ± 0.026 | 0.299 ± 0.066 | 0.0831 |
| Cortical Thickness (mm) | 0.154 ± 0.011 | 0.171 ± 0.012 | 0.0134* |
| Endocortical Perimeter (mm) | 3.69 ± 0.14 | 3.48 ± 0.12 | 0.0100* |
| Length (mm) | 14.74 ± 0.22 | 14.65 ± 0.20 | 0.4388 |
| Marrow Area (mm^2) | 1.083 ± 0.081 | 0.967 ± 0.065 | 0.0101* |
| Maximum Distance from Centroid (mm) | 1.912 ± 0.090 | 1.890 ± 0.082 | 0.6304 |
| Maximum Moment of Inertia (mm^4) | 0.225 ± 0.038 | 0.233 ± 0.032 | 0.6862 |
| Minimum Distance from Centroid (mm) | 1.244 ± 0.046 | 1.213 ± 0.031 | 0.1568 |
| Minimum Moment of Inertia (mm^4) | 0.112 ± 0.016 | 0.110 ± 0.014 | 0.8750 |
| Periosteal Perimeter (mm) | 4.67 ± 0.29 | 4.50 ± 0.22 | 0.2312 |
| Polar Moment of Inertia (mm^4) | 0.337 ± 0.054 | 0.343 ± 0.044 | 0.8114 |
| Pore Area (mm^2) | 0.0017 ± 0.0002 | 0.0022 ± 0.0006 | 0.0424* |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.234 ± 0.029 | 0.246 ± 0.025 | 0.4480 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.179 ± 0.020 | 0.181 ± 0.019 | 0.8056 |
| Tissue Mineral Density (mg/ccm HA) | 1,198.35 ± 9.97 | 1,223.62 ± 9.88 | <0.001* |
| Total Area (mm^2) | 1.77 ± 0.13 | 1.71 ± 0.11 | 0.3788 |