Study Datasets
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Cortical
Microcomputed Tomography (µCT)
1 uploads
Bone: Femur
Region: Trabecular
Microcomputed Tomography (µCT)
1 uploads
Bone: Vertebra
Region: Trabecular
Sample Groups
Nrn1l KO Male
M
12wk
B6N(Cg)-Nrn1l<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Nrn1l KO Female
F
12wk
B6N(Cg)-Nrn1l<tm1.1(KOMP)Vlcg>/J (C57BL/6NTac)
• KO/KO
Nrn1l WT Male
Control
M
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Nrn1l WT Female
Control
F
12wk
C57BL/6NTac (C57BL/6NTac)
• +/+
Analysis Type: Microcomputed Tomography (µCT) Bone: Femur Region: Cortical
| Variable | Nrn1l WT Male (Mean ± SD) | Nrn1l KO Male (Mean ± SD) | T-test (p-Value) |
|---|---|---|---|
| Body Weight (g) | 25.66 ± 1.65 | 25.26 ± 1.53 | 0.6462 |
| Bone Mineral Density (mg/ccm HA) | 1,144.55 ± 8.14 | 1,154.98 ± 9.15 | 0.0407* |
| Cortical Area (mm^2) | 0.734 ± 0.093 | 0.748 ± 0.042 | 0.7253 |
| Cortical Area / Total Area (%) | 39.34 ± 1.28 | 42.83 ± 2.63 | 0.0069* |
| Cortical Mask (dimensionless) | 0.736 ± 0.093 | 0.750 ± 0.042 | 0.7205 |
| Cortical Porosity (%) | 0.278 ± 0.025 | 0.32 ± 0.13 | 0.4793 |
| Cortical Thickness (mm) | 0.159 ± 0.012 | 0.172 ± 0.013 | 0.0723 |
| Endocortical Perimeter (mm) | 3.76 ± 0.25 | 3.54 ± 0.14 | 0.0589 |
| Length (mm) | 14.89 ± 0.29 | 14.75 ± 0.17 | 0.2960 |
| Marrow Area (mm^2) | 1.13 ± 0.15 | 0.998 ± 0.079 | 0.0607 |
| Maximum Distance from Centroid (mm) | 1.96 ± 0.12 | 1.884 ± 0.080 | 0.1812 |
| Maximum Moment of Inertia (mm^4) | 0.252 ± 0.061 | 0.234 ± 0.022 | 0.4794 |
| Minimum Distance from Centroid (mm) | 1.29 ± 0.11 | 1.243 ± 0.041 | 0.3349 |
| Minimum Moment of Inertia (mm^4) | 0.128 ± 0.034 | 0.1162 ± 0.0086 | 0.4104 |
| Periosteal Perimeter (mm) | 4.81 ± 0.44 | 4.58 ± 0.15 | 0.2036 |
| Polar Moment of Inertia (mm^4) | 0.380 ± 0.094 | 0.350 ± 0.029 | 0.4480 |
| Pore Area (mm^2) | 0.0021 ± 0.0004 | 0.0024 ± 0.0011 | 0.4636 |
| Section Modulus about Maximum Moment of Inertia (mm^3) | 0.254 ± 0.047 | 0.248 ± 0.018 | 0.7495 |
| Section Modulus about Minimum Moment of Inertia (mm^3) | 0.196 ± 0.036 | 0.1867 ± 0.0087 | 0.5353 |
| Tissue Mineral Density (mg/ccm HA) | 1,209.27 ± 11.03 | 1,217.70 ± 8.07 | 0.1249 |
| Total Area (mm^2) | 1.87 ± 0.24 | 1.748 ± 0.080 | 0.2358 |